Bioeconomy Science Center
Research and cooperation for a sustainable bioeconomy

Bioeconomy Science Center
Research and cooperation for a sustainable bioeconomy



Schreiber, C, Schiedung, H, Harrison, L, Briese, C, Ackermann, B, Kant, J, Schrey, SD, Hofmann, D, Singh, D, Ebenhöh, O, Amelung, W, Schurr, U, Mettler-Altmann, T, Huber, G, Jablonowski, ND and Nedbal, L (2018). Evaluating potential of green alga Chlorella vulgaris to accumulate phosphorus and to fertilize nutrient-poor soil substrates for crop plants. Journal of Applied Phycology.  AlgalFertilizer

Singh, D, Nedbal, L, and Ebenhöh, O (2017) Modelling phosphorus uptake in microalgae. Biochem Soc Trans 46(2): 483-490. AlgalFertilizer


Borge, L and Bröring, S (2017). Exploring effectiveness of technology transfer in interdisciplinary settings: The case of the bioeconomy. Creativity and Innovation Management 26(3): 311-322.  S2B-BioEcon

Bronikowski, A, Hagedoorn, P-L, Koschorreck, K and Urlacher, VB (2017). Expression of a new laccase from Moniliophthora roreri at high levels in Pichia pastoris and its potential application in micropollutant degradation. AMB Express 7: 73. BioDeg

Damm, T, Grande, PM, Jablonowski, ND, Thiele, B, Disko, U, Mann, U, Schurr, U, Leitner, W, Usadel, B, Domínguez de María, P and Klose, H (2017). OrganoCat pretreatment of perennial plants: Synergies between a biogenic fractionation and valuable feedstocks. Bioresource Technology 244(Part 1): 889-896.  OrCaCel

Damm, T, Pattathil, S, Günl, M, Jablonowski, ND, O'Neill, M, Grün, KS, Grande, PM, Leitner, W, Schurr, U, Usadel, B and Klose, H (2017). Insights into cell wall structure of sida hermaphrodita and its influence on recalcitrance. Carbohydrate Polymers 168: 94-102.   OrCaCel

De Col, V, Fuchs, P, Nietzel, T, Elsasser, M, Voon, CP, Candeo, A, Seeliger, I, Fricker, MD, Grefen, C, Moller, IM, Bassi, A, Lim, BL, Zancani, M, Meyer, AJ, Costa, A, Wagner, S and Schwarzlander, M (2017). ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology. Elife 6.   CoSens

Domröse, A, Weihmann, R, Thies, S, Jaeger, K-E, Drepper, T and Loeschcke, A (2017). Rapid generation of recombinant Pseudomonas putida secondary metabolite producers using yTREX. Synthetic and Systems Biotechnology 2(4): 310-319.   CombiCom

Frantzeskakis, L, Courville, KJ, Plucker, L, Kellner, R, Kruse, J, Brachmann, A, Feldbrugge, M and Gohre, V (2017). The plant-dependent life cycle of thecaphora thlaspeos: A smut fungus adapted to brassicaceae. Mol Plant Microbe Interact: Mpmi08160164r.   PlaMint

Hartl, K, Denton, A, Franz-Oberdorf, K, Hoffmann, T, Spornraft, M, Usadel, B and Schwab, W (2017). Early metabolic and transcriptional variations in fruit of natural white-fruited fragaria vesca genotypes. Sci Rep 7: 45113.    PNP-EXPRESS; MoRe-Plants

Heck, A and Drepper, T (2017). Engineering photosynthetic α-proteobacteria for the production of recombinant proteins and terpenoids. Modern topics in the phototrophic prokaryotes: Environmental and applied aspects. Hallenbeck, P.C. Cham, Springer International Publishing: 395-425.   BIOExpresSPro

Heydenreich, FM, Miljus, T, Jaussi, R, Benoit, R, Milic, D and Veprintsev, DB (2017)High-throughput mutagenesis using a two-fragment PCR approach. Sci Rep 7(1): 6787. RIPE

Hussner, A, Stiers, I, Verhofstad, MJJM, Bakker, ES, Grutters, BMC, Haury, J, van Valkenburg, JLCH, Brundu, G, Newman, J, Clayton, JS, Anderson, LWJ and Hofstra, D (2017). Management and control methods of invasive alien freshwater aquatic plants: A review. Aquatic Botany 136: 112-137.   AquaPro

Jablonowski, ND, Kollmann, T, Nabel, M, Damm, T, Klose, H, Müller, M, Bläsing, M, Seebold, S, Krafft, S, Kuperjans, I, Dahmen, M and Schurr, U (2017). Valorization of sida (sida hermaphrodita) biomass for multiple energy purposes. GCB Bioenergy 9(1): 202-214.   OrCaCel 

Kellner, R and Göhre, V (2017). Thecaphora thlaspeos–ein Brandpilz spezialisiert auf Modellpflanzen. BIOspektrum 23(5): 498-500.  PlaMint

Kessenbrock, M, Klein, SM, Muller, L, Hunsche, M, Noga, G and Groth, G (2017). Novel Protein-Protein Inhibitor Based Approach to Control Plant Ethylene Responses: Synthetic Peptides for Ripening Control. Front Plant Sci 8: 1528. RIPE

Krauss, U, Jager, VD, Diener, M, Pohl, M and Jaeger, KE (2017). Catalytically-active inclusion bodies-Carrier-free protein immobilizates for application in biotechnology and biomedicine. J Biotechnol 258: 136-147. CatIBs

Loeschcke, A, Dienst, D, Wewer, V, Hage-Hulsmann, J, Dietsch, M, Kranz-Finger, S, Huren, V, Metzger, S, Urlacher, VB, Gigolashvili, T, Kopriva, S, Axmann, IM, Drepper, T and Jaeger, KE (2017). The photosynthetic bacteria Rhodobacter capsulatus and Synechocystis sp. PCC 6803 as new hosts for cyclic plant triterpene biosynthesis. PLoS One 12(12): e0189816.   CombiCom

Meurer, RA, Kemper, S, Knopp, S, Eichert, T, Jakob, F, Goldbach, HE, Schwaneberg, U and Pich, A (2017). Biofunctional Microgel-Based Fertilizers for Controlled Foliar Delivery of Nutrients to Plants. Angew Chem Int Ed Engl 56(26): 7380-7386.  RIPEGreenGel

Moudříková, Š, Nedbal, L, Solovchenko, A and Mojzeš, P (2017). Raman microscopy shows that nitrogen-rich cellular inclusions in microalgae are microcrystalline guanine. Algal Research 23: 216-222.   AlgalFertilizer

Moudrikova, S, Sadowsky, A, Metzger, S, Nedbal, L, Mettler-Altmann, T and Mojzes, P (2017). Quantification of Polyphosphate in Microalgae by Raman Microscopy and by a Reference Enzymatic Assay. Anal Chem 89(22): 12006-12013.   AlgalFertilizer

Pompa, A, De Marchis, F, Pallotta, MT, Benitez-Alfonso, Y, Jones, A, Schipper, K, Moreau, K, Zarsky, V, Di Sansebastiano, GP and Bellucci, M (2017)
. Unconventional transport routes of soluble and membrane proteins and their role in developmental biology. Int J Mol Sci 18(4).   UstiOpt

Reinicke, S, Rees, HC, Espeel, P, Vanparijs, N, Bisterfeld, C, Dick, M, Rosencrantz, RR, Brezesinski, G, de Geest, BG, Du Prez, FE, Pietruszka, J and Boker, A (2017). Immobilization of 2-deoxy-d-ribose-5-phosphate aldolase in polymeric thin films via the langmuir-schaefer technique. ACS Appl Mater Interfaces 9(9): 8317-8326.   FlowCom

Terfrüchte, M, Reindl, M, Jankowski, S, Sarkari, P, Feldbrügge, M and Schipper, K (2017). Applying unconventional secretion in ustilago maydis for the export of functional nanobodies. International Journal of Molecular Sciences 18(5): 937.  UstiOpt

Welters, T, Horn, T, Ruff, AJ, Schwaneberg, U and Buchs, J (2017). Novel technique for high throughput measurement of active monooxygenase concentration. Biotechnol Bioeng 114(4): 929-933.   MoRe-Plants

Worgull, D, Öhler, L, Strache, JP, Friedrichs, T, and Ullrich, P (2017) Enantioselective synthesis of 2,3-dihydrofurans via ammonium ylides. Eur J Org Chem, 6077-6080. PrimACs

Zambanini, T, Hartmann, SK, Schmitz, LM, Büttner, L, Tehrani, HH, Geiser, E, Beudels, M, Venc, D, Wandrey, G, Büchs, J, Schwarzländer, M, Blank, LM, and Wierckx, N (2017)   Promoters from the itaconate cluster of Ustilago maydis are induced by nitrogen depletion. Fungal Biol Biotechnol 4:11.  ROXENSE

Zhao, X, Noack, S, Wiechert, W and Lieres, EV (2017). Dynamic flux balance analysis with nonlinear objective function. J Math Biol.   BEProMod



Alexander, A and Hunsche, M (2016). Influence of formulation on the cuticular penetration and on spray deposit properties of manganese and zinc foliar fertilizers. Agronomy 6(3): 39.   BiFuProts 

Bisterfeld, C, Küberl, I, Dick, M and Pietruszka, J (2016). A fluorogenic screening for enantio- and diastereoselectivity of 2-deoxy-d-ribose-5-phosphate aldolases. Synlett 27(01): 11-16.   FlowCom

Bosch, K, Frantzeskakis, L, Vranes, M, Kamper, J, Schipper, K and Gohre, V (2016). Genetic manipulation of the plant pathogen ustilago maydis to study fungal biology and plant microbe interactions. J Vis Exp(115).   PlaMint

Damm, T, Commandeur, U, Fischer, R, Usadel, B and Klose, H (2016). Improving the utilization of lignocellulosic biomass by polysaccharide modification. Process Biochemistry 51(2): 288-296.   OrCaCel

Dick, M, Hartmann, R, Weiergraber, OH, Bisterfeld, C, Classen, T, Schwarten, M, Neudecker, P, Willbold, D and Pietruszka, J (2016). Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: Structural insights and protective strategies. Chemical Science 7(7): 4492-4502.   FlowCom

Dick, M, Weiergräber, OH, Classen, T, Bisterfeld, C, Bramski, J, Gohlke, H and Pietruszka, J (2016). Trading off stability against activity in extremophilic aldolases. Scientific Reports 6: 17908.   FlowCom

Diener, M, Kopka, B, Pohl, M, Jaeger, K-E and Krauss, U (2016). Fusion of a coiled-coil domain facilitates the high-level production of catalytically active enzyme inclusion bodies. ChemCatChem 8(1): 142-152.   CatIBs

Freier, L, Hemmerich, J, Schöler, K, Wiechert, W, Oldiges, M and von Lieres, E (2016). Framework for kriging-based iterative experimental analysis and design: Optimization of secretory protein production in corynebacterium glutamicum. Engineering in Life Sciences 16(6): 538-549.   BIOExpresSPro

Geiser, E, Ludwig, F, Zambanini, T, Wierckx, N and Blank, LM (2016). Draft genome sequences of itaconate-producing ustilaginaceae. Genome Announc 4(6).   PectiLyse

Geiser, E, Przybilla, SK, Engel, M, Kleineberg, W, Buttner, L, Sarikaya, E, Hartog, TD, Klankermayer, J, Leitner, W, Bolker, M, Blank, LM and Wierckx, N (2016). Genetic and biochemical insights into the itaconate pathway of ustilago maydis enable enhanced production. Metab Eng 38: 427-435.  

Geiser, E, Reindl, M, Blank, LM, Feldbrugge, M, Wierckx, N and Schipper, K (2016). Activating intrinsic carbohydrate-active enzymes of the smut fungus ustilago maydis for the degradation of plant cell wall components. Appl Environ Microbiol 82(17): 5174-5185.   UstiLyse

Hemmerich, J, Rohe, P, Kleine, B, Jurischka, S, Wiechert, W, Freudl, R and Oldiges, M (2016). Use of a sec signal peptide library from bacillus subtilis for the optimization of cutinase secretion in corynebacterium glutamicum. Microbial Cell Factories 15(1): 208.   BIOExpresSPro

Hoffmann, AM, Noga, G and Hunsche, M (2016). Alternating high and low intensity of blue light affects psii photochemistry and raises the contents of carotenoids and anthocyanins in pepper leaves. Plant Growth Regulation 79(3): 275-285.   InducTomE 

Kosciow, K, Domin, C, Schweiger, P and Deppenmeier, U (2016). Extracellular targeting of an active endoxylanase by a tolb negative mutant of gluconobacter oxydans. J Ind Microbiol Biotechnol 43(7): 989-999.   GLUFACT

Lenders, MH, Beer, T, Smits, SH and Schmitt, L (2016). In vivo quantification of the secretion rates of the hemolysin a type i secretion system. Sci Rep 6: 33275.   BioBreak

Li, Z, Omranian, N, Neumetzler, L, Wang, T, Herter, T, Usadel, B, Demura, T, Giavalisco, P, Nikoloski, Z and Persson, S (2016). A transcriptional and metabolic framework for secondary wall formation in arabidopsis. Plant Physiol 172(2): 1334-1351.   OrCaCel 

Lotz, J, Schwalbach, M and Naumann, U (2016). A case study in adjoint sensitivity analysis of parameter calibration. Procedia Computer Science 80: 201-211.   BEProMod 

MacKellar, D, Lieber, L, Norman, JS, Bolger, A, Tobin, C, Murray, JW, Oksaksin, M, Chang, RL, Ford, TJ, Nguyen, PQ, Woodward, J, Permingeat, HR, Joshi, NS, Silver, PA, Usadel, B, Rutherford, AW, Friesen, ML and Prell, J (2016). Streptomyces thermoautotrophicus does not fix nitrogen. Scientific Reports 6: 20086.   BIOExpresSPro

Nguyen, GT, Erlenkamp, G, Jack, O, Kuberl, A, Bott, M, Fiorani, F, Gohlke, H and Groth, G (2016). Chalcone-based selective inhibitors of a c4 plant key enzyme as novel potential herbicides. Sci Rep 6: 27333.   C4-PSH

Safiran, N, Lotz, J and Naumann, U (2016). Algorithmic differentiation of numerical methods: Second-order adjoint solvers for parameterized systems of nonlinear equations. Procedia Computer Science 80: 2231-2235.   BEProMod

Sarkari, P, Feldbrügge, M and Schipper, K (2016). The corn smut fungus ustilago maydis as an alternative expression system for biopharmaceuticals. Gene expression systems in fungi: Advancements and applications. Schmoll, M. and Dattenböck, C. Cham, Springer International Publishing: 183-200.   UstiOpt

Solovchenko, A, Verschoor, AM, Jablonowski, ND and Nedbal, L (2016). Phosphorus from wastewater to crops: An alternative path involving microalgae. Biotechnol Adv 34(5): 550-564.   AlgalFertilizer

Stock, J, Terfruchte, M and Schipper, K (2016). A reporter system to study unconventional secretion of proteins avoiding n-glycosylation in ustilago maydis. Methods Mol Biol 1459: 149-160.   UstiOpt

Voiniciuc, C, Zimmermann, E, Schmidt, MH, Gunl, M, Fu, L, North, HM and Usadel, B (2016). Extensive natural variation in arabidopsis seed mucilage structure. Front Plant Sci 7: 803.   EnZIP

Witzel, C-P and Finger, R (2016). Economic evaluation of miscanthus production – a review. Renewable and Sustainable Energy Reviews 53(C): 681-696.   MisCas

Zahid, N and Deppenmeier, U (2016). Role of mannitol dehydrogenases in osmoprotection of gluconobacter oxydans. Appl Microbiol Biotechnol 100(23): 9967-9978.   GLUFACT



Domrose, A, Klein, AS, Hage-Hulsmann, J, Thies, S, Svensson, V, Classen, T, Pietruszka, J, Jaeger, KE, Drepper, T and Loeschcke, A (2015). Efficient recombinant production of prodigiosin in pseudomonas putida. Front Microbiol 6: 972.   LIPANO

Grande, PM, Viell, J, Theyssen, N, Marquardt, W, Dominguez de Maria, P and Leitner, W (2015). Fractionation of lignocellulosic biomass using the organocat process. Green Chemistry 17(6): 3533-3539.   OrCaCel

Kiefler, I, Bringer, S and Bott, M (2015). Sdhe-dependent formation of a functional acetobacter pasteurianus succinate dehydrogenase in gluconobacter oxydans--a first step toward a complete tricarboxylic acid cycle. Appl Microbiol Biotechnol 99(21): 9147-9160.   GLUFACT

Klose, H, Gunl, M, Usadel, B, Fischer, R and Commandeur, U (2015). Cell wall modification in tobacco by differential targeting of recombinant endoglucanase from trichoderma reesei. BMC Plant Biol 15: 54.   EnZIP

Lang, V, Usadel, B and Obermeyer, G (2015). De novo sequencing and analysis of the lily pollen transcriptome: An open access data source for an orphan plant species. Plant Mol Biol 87(1-2): 69-80.   PNP-EXPRESS

Loeschcke, A and Thies, S (2015). Pseudomonas putida-a versatile host for the production of natural products. Appl Microbiol Biotechnol 99(15): 6197-6214.   LIPANO

Lotz, J, Naumann, U, Hannemann-Taḿas, R, Ploch, T and Mitsos, A (2015). Higher-order discrete adjoint ode solver in c++ for dynamic optimization. Procedia Computer Science 51: 256-265.   BEProMod

Luchterhand, B, Fischoder, T, Grimm, AR, Wewetzer, S, Wunderlich, M, Schleputz, T and Buchs, J (2015). Quantifying the sensitivity of g. Oxydans atcc 621h and dsm 3504 to osmotic stress triggered by soluble buffers. J Ind Microbiol Biotechnol 42(4): 585-600.   GLUFACT

María, PDd, Grande, PM and Leitner, W (2015). Current trends in pretreatment and fractionation of lignocellulose as reflected in industrial patent activities. Chemie Ingenieur Technik 87(12): 1686-1695.   OrCaCel

Meyer, M, Schweiger, P and Deppenmeier, U (2015). Succinic semialdehyde reductase gox1801 from gluconobacter oxydans in comparison to other succinic semialdehyde-reducing enzymes. Appl Microbiol Biotechnol 99(9): 3929-3939.   GLUFACT

Moseler, A, Aller, I, Wagner, S, Nietzel, T, Przybyla-Toscano, J, Muhlenhoff, U, Lill, R, Berndt, C, Rouhier, N, Schwarzlander, M and Meyer, AJ (2015). The mitochondrial monothiol glutaredoxin s15 is essential for iron-sulfur protein maturation in arabidopsis thaliana. Proc Natl Acad Sci U S A 112(44): 13735-13740.   CoSens

Torra, J, Burgos-Caminal, A, Endres, S, Wingen, M, Drepper, T, Gensch, T, Ruiz-Gonzalez, R and Nonell, S (2015). Singlet oxygen photosensitisation by the fluorescent protein pp2fbfp l30m, a novel derivative of pseudomonas putida flavin-binding pp2fbfp. Photochem Photobiol Sci 14(2): 280-287.   BIOExpresSPro

van Summeren-Wesenhagen, PV and Marienhagen, J (2015). Metabolic engineering of escherichia coli for the synthesis of the plant polyphenol pinosylvin. Appl Environ Microbiol 81(3): 840-849.   PNP-EXPRESS

van Summeren-Wesenhagen, PV, Voges, R, Dennig, A, Sokolowsky, S, Noack, S, Schwaneberg, U and Marienhagen, J (2015). Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with escherichia coli. Microb Cell Fact 14: 79.   PNP-EXPRESS

Voiniciuc, C, Gunl, M, Schmidt, MH and Usadel, B (2015). Highly branched xylan made by irregular xylem14 and mucilage-related21 links mucilage to arabidopsis seeds. Plant Physiol 169(4): 2481-2495.   EnZIP

Voiniciuc, C, Schmidt, MH, Berger, A, Yang, B, Ebert, B, Scheller, HV, North, HM, Usadel, B and Gunl, M (2015). Mucilage-related10 produces galactoglucomannan that maintains pectin and cellulose architecture in arabidopsis seed mucilage. Plant Physiol 169(1): 403-420.   EnZIP

Wang, H, Paulo, J, Kruijer, W, Boer, M, Jansen, H, Tikunov, Y, Usadel, B, van Heusden, S, Bovy, A and van Eeuwijk, F (2015). Genotype-phenotype modeling considering intermediate level of biological variation: A case study involving sensory traits, metabolites and qtls in ripe tomatoes. Mol Biosyst 11(11): 3101-3110.   PNP-EXPRESS



Kosciow, K, Zahid, N, Schweiger, P and Deppenmeier, U (2014). Production of a periplasmic trehalase in gluconobacter oxydans and growth on trehalose. J Biotechnol 189: 27-35.   GLUFACT

Loehrer, M, Vogel, A, Huettel, B, Reinhardt, R, Benes, V, Duplessis, S, Usadel, B and Schaffrath, U (2014). On the current status of phakopsora pachyrhizi genome sequencing. Front Plant Sci 5: 377.   GLUFACT; BIOExpresSPro

Noack, S and Wiechert, W (2014). Quantitative metabolomics: A phantom? Trends Biotechnol 32(5): 238-244.  

Paulus, JK, Forster, K and Groth, G (2014). Direct and selective small-molecule inhibition of photosynthetic pep carboxylase: New approach to combat c4 weeds in arable crops. FEBS Lett 588(12): 2101-2106.   C4-PSH

Terfruchte, M, Joehnk, B, Fajardo-Somera, R, Braus, GH, Riquelme, M, Schipper, K and Feldbrugge, M (2014). Establishing a versatile golden gate cloning system for genetic engineering in fungi. Fungal Genet Biol 62: 1-10.  

Zeiser, J, Muhlenbeck, LH, Schweiger, P and Deppenmeier, U (2014). Characterization of a periplasmic quinoprotein from sphingomonas wittichii that functions as aldehyde dehydrogenase. Appl Microbiol Biotechnol 98(5): 2067-2079.



Feldbrugge, M, Kellner, R and Schipper, K (2013)The biotechnological use and potential of plant pathogenic smut fungi. Appl Microbiol Biotechnol 97(8): 3253-3265.  

Geiser, E, Wierckx, N, Zimmermann, M and Blank, LM (2013). Identification of an endo-1,4-beta-xylanase of ustilago maydis. BMC Biotechnol 13: 59.