Forschen • Ausbilden • Vernetzen
Für eine nachhaltige Bioökonomie

Forschen • Ausbilden • Vernetzen
Für eine nachhaltige Bioökonomie

CombiCom Publikationen


Hogenkamp, F., et al. (2021). "Effect of Photocaged Isopropyl β-d-1-thiogalactopyranoside Solubility on the Light Responsiveness of LacI-controlled Expression Systems in Different Bacteria." Chembiochem : a European journal of chemical biology 22(3): 539-547.



Baum, C. M. and B. Bartkowski (2020). "It’s not all about funding: Fostering interdisciplinary collaborations in sustainability research from a European perspective." Energy Research & Social Science 70: 101723

Brands S, Brass HUC, Klein AS, Pietruszka J, Ruff AJ, and Schwaneberg U (2020) A colourimetric high-throughput screening system for directed evolution of prodigiosin ligase PigC. Chem. Commun. doi:10.1039/D0CC02181D.

Butkowski OK, Baum CM, Pakseresht A, Bröring S, Lagerkvist CJ (2020) Examining the social acceptance of genetically modified bioenergy in Germany: Labels, information valence, corporate actors, and consumer decisions. Energy Research & Social Science 60:101308. doi: 10.1016/j.erss.2019.101308

Fejzagić, A. V., et al. (2020). "A Fluorescence-Based Assay System for the Determination of Haloperoxidase-Activity Using a Two-Dimensional Calibration Ap-proach." ChemistryOpen 9(9): 959-966.

Habash, S. S., et al. (2020). "Novel Prodiginine Derivatives Demonstrate Bioactivities on Plants, Nematodes, and Fungi." Front Plant Sci 11: 579807-579807.
Habash, S. S., et al. (2020). "The Plant Sesquiterpene Nootkatone Efficiently Reduces Heterodera schachtii Parasitism by Activating Plant Defense." Int J Mol Sci 21(24): 9627.
Harwoko, H., et al. (2020). "Azacoccones F-H, new flavipin-derived alkaloids from an endophytic fungus Epicoccum nigrum MK214079." Fitoterapia 146: 104698.

Lee J, Hilgers F, Loeschke A, Jaeger K-E, and Feldbrügge M (2020) Ustilago maydis serves as a novel production host for the synthesis of plant and fungal sesquiterpenoids. Front. Microbiol., doi: 10.3389/fmicb.2020.01655

Lee, J., et al. (2020). "Identification of Feldin, an Antifungal Polyyne from the Beefsteak Fungus Fistulina hepatica."  10(11): 1502.

Loeschcke A, Thies S (2020) Engineering of natural product biosynthesis in Pseudomonas putida. Curr Opin Biotechnol. 65:213–224.

Müntjes K, Philipp M, Hüsemann L, Heucken N, Weidtkamp-Peters S, Schipper K, Zurbriggen MD and Feldbrügge M (2020) Establishing Polycistronic Expression in the Model Microorganism Ustilago maydis. Front. Microbiol. 11:1384.

Pan F, EI-Kashef D, Kalscheuer R, Müller WEG, Lee J, Feldbrügge M, Mándi A, Kurtán T, Liu Z, Wu W, Proksch P (2020) Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017. Eur. J. Med. Chem. 191: 113159.

Weihmann R, Domröse A, Drepper T, Jaeger KE, Loeschcke A (2020) Protocols for yTREX/Tn5-based gene cluster expression in Pseudomonas putida. Microb Biotechnol. 13(1):250-262.



Baum CM (2019). When Technology and Reality Meet: Exploring the Potential of a Constructive Precautionary Principle for Genome-Editing Technologies. In C. Dürnberger, S. Pfeilmeier, & S. Schleissing (Eds.), Genome Editing in Agriculture. Between Precaution and Responsibility (pp. 197-211). TTN-Studien Volume 7. Baden-Baden: Nomos. ISBN: 978-3-8487-5518-9.

Bartkowski, B. & Baum C.M. (2019) Dealing With Rejection: An Application of the Exit–Voice Framework to Genome-Edited Food. Frontiers in Bioengineering and Biotechnology 7:57. doi: 10.3389/fbioe.2019.00057.

Brass HUC, Klein AS, Nyholt S, Classen T, Pietruszka J (2019) Condensing Enzymes from Pseudoalteromonadaceae for Prodiginine Synthesis. Adv. Synth. Catal.361(11):2659-2667.

Burmeister, A., et al. (2019). "A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments." Lab on a Chip 19(1): 98-110.

Domröse A, Hage-Hülsmann J, Thies S, Weihmann R, Kruse L, Otto M, Wierckx N, Jaeger KE, Drepper T, Loeschcke A (2019) Pseudomonas putida rDNA is a favored site for the expression of biosynthetic genes. Sci Rep. 9(1):7028.

Fejzagić AV, Gebauer J, Huwa N, Classen T (2019) Halogenating Enzymes for Active Agent Synthesis: First Steps Are Done and Many Have to Follow. Molecules 24(21):4008.

Hage-Hülsmann J, Metzger S, Wewer V, Buechel F, Troost K, Thies S, Loeschcke A., Jaeger K-E, Drepper T (2019) Biosynthesis of cycloartenol by expression of plant and bacterial oxidosqualene cyclases in engineered Rhodobacter capsulatus. J Biotechnol X 4: 100014.

Harwoko H, Daletos G, Stuhldreier F, Lee J, Wesselborg S, Feldbrügge M, Müller WEG, Kalscheuer R, Ancheeva E, Proksch P (2019) Dithiodiketopiperazine derivatives from endophytic fungi Trichoderma harzianum and Epicoccum nigrum. Nat. Prod. Res. 18:1-9.

Hilgers, F., et al. (2019). "Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents." Int J Mol Sci 20(18): 4608

Kallscheuer N, Classen T, Drepper T, Marienhagen J (2019) Production of plant metabolites with applications in the food industry using engineered microorganisms. Curr Opin Biotechnol. 56:7-17.

Nogueira M, Enfissi EMA, Welsch R, Beyer P, Zurbriggen MD, Fraser PD (2019) Construction of a fusion enzyme for astaxanthin formation and its characterization in microbial and plant hosts: A new tool for engineering ketocarotenoids. Metabolic Engineering 52:243-252. doi: 10.1016/j.ymben.2018.12.006.

Otto M, Wynands B, Drepper T, Jaeger K-E, Thies S, Loeschcke A, Blank LM, Wierckx N (2019). Targeting 16S rDNA for Stable Recombinant Gene Expression in Pseudomonas. ACS Synth Biol 8(8):1901 – 1912.

Troost K, Loeschcke A, Hilgers F, Özgür AY, Weber TM, Santiago-Schübel B, Svensson V, Hage-Hülsmann J, Habash SS, Grundler FMW, Schleker S, Jaeger K-E, Drepper T (2019). Engineered Rhodobacter capsulatus as a phototrophic platform organism for the synthesis of plant sesquiterpenoids. Front Microbiol. 10: 1998.



Baaske J, Gonschorek P, Engesser R, Dominguez-Monedero A, Raute K, Fischbach P, Müller K, Cachat E, Schamel WWA, Minguet S, Davies J, Timmer J, Weber W, Zurbriggen MD. (2018). Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells. Scientific Reports. 8(1):15024.

Beyer HM, Engesser R, Hörner M, Koschmieder J, Beyer P, Timmer J, Zurbriggen MD, Weber W (2018) Synthetic Biology Makes Polymer Materials Count. Advanced Materials 30(21):e1800472

Beyer HM, Thomas OS, Riegel N, Zurbriggen MD, Weber W, Hörner M (2018) Generic and reversible opto-trapping of biomolecules. Acta Biomaterialia 79: 276-282.

Chatelle C, Ochoa-Fernandez R, Engesser R, Schneider N, Beyer HM, Jones AR, Timmer J, Zurbriggen MD, Weber W (2018). A Green-Light-Responsive System for the Control of Transgene Expression in Mammalian and Plant Cells. ACS Synthetic Biology 7(5):1349-1358.

Classen T, Pietruszka J (2018) Complex molecules, clever solutions - enzymatic approaches towards natural product and active agent syntheses. Bioorg Med Chem. 26(7):1285-1303.

Endres S, Wingen M, Torra J, Ruiz-González R, Polen T, Bosio G, Bitzenhofer NL, Hilgers F, Gensch T, Nonell S, Jaeger K-E, Drepper T (2018) An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria. Scientific Reports 8(1):15021.

Hage-Hülsmann J, Grünberger A, Thies S, Santiago-Schübel B, Klein AS, Pietruszka J, Binder D, Hilgers F, Domröse A, Drepper T, Kohlheyer D, Jaeger K-E, Loeschcke A (2018). Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactants. PLoS ONE 13(7): e0200940.

Klein AS, Brass HUC, Klebl DP, Classen T, Loeschcke A, Drepper T, Sievers S, Jaeger K-E, Pietruszka J (2018) Preparation of cyclic prodiginines by mutasynthesis in Pseudomonas putida KT2440. ChemBioChem 19(14):1545-1552.



Domröse A, Weihmann R, Thies S,  Jaeger K-E, Drepper T, Loeschcke A (2017) Rapid generation of recombinant Pseudomonas putida secondary metabolite producers using yTREX, Synth Syst Biotechnol. 2(4):310-319.

Klein AS, Domröse A, Bongen P, Brass HUC, Classen T, Loeschcke A, Drepper T, Laraia L, Sievers S, Jaeger KE, Pietruszka J (2017). New Prodigiosin Derivatives Obtained by Mutasynthesis in Pseudomonas putida. ACS Synthetic Biology 6(9):1757–1765.

Loeschcke A, Dienst D, Wewer V, Hage-Hülsmann J, Dietsch M, Kranz-Finger S, Hüren V, Metzger S, Urlacher VB, Gigolashvili T, Kopriva S, Axmann IM, Drepper T, Jaeger K-E (2017) The photosynthetic bacteria Rhodobacter capsulatus and Synechocystis sp. PCC 6803 as new hosts for cyclic plant triterpene biosynthesis. PLoS ONE 12(12):e0189816.