Bioeconomy Science Center
Research and cooperation for a sustainable bioeconomy

Bioeconomy Science Center
Research and cooperation for a sustainable bioeconomy

7th BioSC Spotlight

"Modular biotransformations in a circular bioeconomy"

February 5, 2020 | 10:30 am - 5:00 pm | RWTH Aachen

NGP2 - Center for Next Generation Processes and Products | Forckenbeckstr. 51 | 52074 Aachen

Photos: HHU Düsseldorf, RWTH Aachen University


The production of bulk and fine chemicals in a circular bioeconomy will be characterized by new process chains where biotransformations will play an important role. Biogenic raw materials will cover a wide range of qualities and quantities, from perennial biomass to agricultural waste streams, complemented by non-biogenic carbon sources such as CO2 or plastic waste. To deal with this broad spectrum, the conventional „One substrate – one product“ way of production needs to be evolved to complex „Multi substrate – multi product“ process chains where classical chemical transformations and biotransformations are combined. Tailored biosynthetic pathways for the production of high-value compounds can be developed with the tools of Synthetic Biology. The entire transformation process also requires the development of integrated and flexible biorefinery concepts. In order to generate the highest possible added value and ensure the efficient use of raw materials, a holistic process approach is of great interest. In the frame of the 7th BioSC Spotlight, current developments will be presented and discussed by BioSC scientists and external experts.


Registration is closed.




Welcome and Introduction

Prof. Dr. Wolfgang Wiechert (Forschungszentrum Jülich/ BioSC)



From Carbon Streams to Precursors

Session Chair: Dr. Stephan Noack (Forschungszentrum Jülich/ BioSC)


From lignin to central metabolites – key questions and some insight from a five year project
Prof. Dr. Gunnar Lidén, Lund University

Bio-upcycling of PET into value-added chemicals
Maike Otto, Forschungszentrum Jülich/ BioSC

Extending the menu of a pampered industrial bug to create new value chains
Niklas Tenhaef, Forschungszentrum Jülich/ BioS




Microbial Production of Bulk Chemicals

Session Chair: Dr. Nina Ihling (RWTH Aachen University/ BioSC)


Microbial Production of Mannosylerythritol- and Cellobioselipids
Dr. Susanne Zibek, Fraunhofer IGB, Stuttgart

Efficient downstream processes for recovery and purification of bio-based bulk chemicals from fermentation supernatant
Andreas Biselli, RWTH Aachen University/ BioSC
Christian Kocks, RWTH Aachen University/ BioSC

Construction of bacterial cell factories for heterologous rhamnolipid production
Isabel Bator, RWTH Aachen University/ BioSC
Sonja Kubicki, HHU Düsseldorf / BioSC

14:45 Coffee break
SynBio-Based Production of Fine Chemicals

Session Chair: Dr. Anita Loeschcke (HHU Düsseldorf/ BioSC)


Microbial synthesis of terpenoids – transport issues and structure space expansion strategies
Dr. Markus Buchhaupt, DECHEMA Research Institute, Frankfurt am Main

Engineering cyanobacteria towards balanced triterpene biosynthesis
Prof. Dr. Ilka Maria Axmann, HHU Düsseldorf/BioSC

Pseudomonas putida-based production of diverse fine chemicals
Dr. Anita Loeschcke, HHU Düsseldorf/BioSC
Hannah Braß, HHU Düsseldorf/BioSC


Closing remarks

Prof. Dr. Wolfgang Wiechert (Forschungszentrum Jülich/ BioSC)



Guided tours through the NGP2 biorefinery